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Clinipath Services Limited

Address: 217/3, Marina Street,
Pieta, PTA 9041,
MALTA
Phone: 00356 21 221 355
Mobile: 00356 99 852 404
Fax: 00356 21 233 160
Email: info@clinipath.com.mt

Contact persons:

Dr Stefan Laspina MD, FF Path, FRCPath
Pathologist
Mob: 99296046

Alex Gingell
Laboratory Director
Mob: 99430612

Prof A. Cilia Vincenti MD, FRCPath
Cyto-/Histo-pathologist
Mob: 79441707

Clinic Hours:

Monday to Friday
8a.m. to 6p.m.

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12-07-2016 | GLYCATED HAEMOGLOBIN (HbA1c)

HbA1c – DCCT / IFCC / eAG Relationship

Up to recent years, the HbA1c (glycated haemoglobin) was reported as a percentage in accordance to “The Diabetes Control and Complications Trial” (DCCT).  The situation has changed as a result of a number of standardisation programmes, culminating in the work of the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) Working Group on Standardisation of HbA1c, which established true International Reference Methods.  Hence, HbA1c results, traceable to the IFCC reference method derived, will be expressed as mmol per mol of unglycated haemoglobin.

In additon, a large international study recently produced equivalent “average glucose” (eAG) values for HbA1c expressed in mmol per Litre. This eAG, like the HbA1c, shows an estimation of the glucose levels in the preceding 2 – 3 months.

In the forthcoming weeks, Clinipath will start reporting HbA1c results in both DCCT (%) and IFCC (mmol/mol), as well in eAG (mmol/L).

Reference Ranges

                                                IFCC                                                       DCCT                                     eAG

Non-diabetic     :               20 – 42 mmol/mol                           4.0 – 6.0 %                           3.8 – 7.0 mmol/L

Pre-diabetes      :             43 – 47                                                    6.1 – 6.4                               7.1 – 7.6

Diabetes             :              > 48                                                         > 6.5                                      > 7.7

 

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